The plasma HGH concentrations were assayed in total 138 cases by the radioimmunoassay. The groups of control, typhoid fever, epidemic hemorrhagic fever, tuberculous meningitis and other febrile diseases were studied, also were the groups of hyperthyroidism, acromegaly and hypopitutarism. Insulin. stimulation test was performed in control, typhoid fever and hypopituitarism.
In the control group, the plasma HGH concentration in fasting (early morning) was 206±1.´183 mpg/ml and its upper limit was 4.5 mpg/ail. No sexual difference was observed. -By the insulin stimulation, plasma HGH concentration had rised to the peak` level of 24.1±15.71 mpg/m1, 60 ?mnn:´affer-- - the intravenous insulin injection, theri decreased to the -normal level progressively.
In typhoid fever, fasting HGH concentrations in- febrile "state and in defeverence were 2-5±1.-35 - mpg/ml ´and 2;2±3. 32 mμg/ml respectively,´ showing no significant difference, with the control group. ; However, ´the -levels c individual cases ranged widely, -compared with the control ´The response´=´´
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to the´ insulin stimulation test was similar to the control group.
In epidemic hemorrvhTagid fever: the HGH concentrations in oliguric phase, in- diuretic phase and in convalescence were 4.`2±-3.711 mpg/ml, -2 2±1. 30 mpg/ml and 3. 4±3. 01 mpg/ml respectively. No significant differences were obscr´e´ v´ ~n compared to the control, but they showed vide range of plasma HGH levels
-In´ tuberculous´ meningitis the fasting´ HGH concentration w"´2. 9±1.42 mpg/ml.
In the other febrile´- diseases, the value was 2.5±2.23 mpg/ml. -
In 4 cases of hypopituitarism, the fasting 7HGH concentration was 2.3±0.42 mpg/ml and ranged normally. However, the response to the insulin stimulation test-was not observed. Very` high plasma´" HGH concentrations were observed in acromegalic patients.
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